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Cecilio Valadez-Cano

Integrating Omics and Bioinformatics to Study Microbial Communities

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Anatoxin biosynthesis gene abundance correlates with anatoxin concentration in freshwater benthic samples


Journal article


Joshua R. Evans, Daniel G. Beach, Jake Stillwell, Meghann Bruce, Adrian Reyes-Prieto, Cecilio Valadez-Cano, Pearse McCarron, Janice Lawrence
Toxicon, vol. 273, 2026, p. 109011


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APA   Click to copy
Evans, J. R., Beach, D. G., Stillwell, J., Bruce, M., Reyes-Prieto, A., Valadez-Cano, C., … Lawrence, J. (2026). Anatoxin biosynthesis gene abundance correlates with anatoxin concentration in freshwater benthic samples. Toxicon, 273, 109011. https://doi.org/10.1016/j.toxicon.2026.109011


Chicago/Turabian   Click to copy
Evans, Joshua R., Daniel G. Beach, Jake Stillwell, Meghann Bruce, Adrian Reyes-Prieto, Cecilio Valadez-Cano, Pearse McCarron, and Janice Lawrence. “Anatoxin Biosynthesis Gene Abundance Correlates with Anatoxin Concentration in Freshwater Benthic Samples.” Toxicon 273 (2026): 109011.


MLA   Click to copy
Evans, Joshua R., et al. “Anatoxin Biosynthesis Gene Abundance Correlates with Anatoxin Concentration in Freshwater Benthic Samples.” Toxicon, vol. 273, 2026, p. 109011, doi:10.1016/j.toxicon.2026.109011.


BibTeX   Click to copy

@article{evans2026a,
  title = {Anatoxin biosynthesis gene abundance correlates with anatoxin concentration in freshwater benthic samples},
  year = {2026},
  journal = {Toxicon},
  pages = {109011},
  volume = {273},
  doi = {10.1016/j.toxicon.2026.109011},
  author = {Evans, Joshua R. and Beach, Daniel G. and Stillwell, Jake and Bruce, Meghann and Reyes-Prieto, Adrian and Valadez-Cano, Cecilio and McCarron, Pearse and Lawrence, Janice}
}

Abstract

The abundance of the anaC gene, which is involved in anatoxin biosynthesis, correlated with anatoxin concentration (rs = 0.80, p < 0.0001) in Atlantic Canadian benthic freshwater samples. Average total anatoxins (100 μg g−1 by high resolution mass spectrometry) and anaC (4.7 x 108 copies g−1 by droplet digital PCR) were highest in August, while highest average toxin quota (8.9 pg anaC−1) was observed in July. Pairing approaches provided insight into the seasonality of anatoxin biosynthesis. 

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